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 nsp3cSUD

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N/A
Putative protease
Not Known
Not Known

 Introduction

The region corresponding to residues 365 to 722 has been considered a domain unique to SARS-CoV and is called the SUD (SARS Unique Domain). The corresponding regions (just downstream of the ADRP domain) in HCoV-NL63, PEDV, HCoV-229E (among Group 1 viruses) and all Group 2 viruses have no assigned domain prediction.

The SUD has been expressed in E. coli and appears to have autoproteolytic activity and a co-factor.

 

Reference:

http://www.egms.de/en/meetings/sars2004/04sars130.shtml

 

 
 
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 Links

  Link to SARS-SUD Metal binding and protease activity